Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 4/20 | 0.47 |
| ▸ | CMA1 | P23946 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PRSS8 | Q16651 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466056 | 0.90 | DAGLA (0.45) | DAGLAFAAHCES1XDHCMA1 | |
| SCHEMBL6465885 | 0.88 | XDH (0.47) | DAGLAFAAHCES1XDHELANE | |
| SCHEMBL6463425 | 0.87 | DAGLA (0.43) | DAGLAFAAHCES1XDHCMA1 | |
| SCHEMBL6468626 | 0.84 | CTSS (0.44) | DAGLAFAAHCES1XDHLMNA | |
| SCHEMBL6463414 | 0.84 | CTSS (0.44) | DAGLAFAAHCES1XDHLMNA | |
| SCHEMBL6464297 | 0.82 | DAGLA (0.44) | DAGLAFAAHCES1XDHCMA1 | |
| SCHEMBL5523159 | 0.81 | DAGLA (0.56) | DAGLAFAAHCES1XDHELANE | |
| SCHEMBL6463433 | 0.76 | DAGLA (0.42) | DAGLAFAAHCES1XDHCMA1 | |
| SCHEMBL6465103 | 0.74 | FAAH (0.41) | DAGLAFAAHCES1XDH | |
| SCHEMBL6471948 | 0.74 | CTSS (0.50) | DAGLAFAAHCES1XDHCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |