SCHEMBL6465215

SCHEMBL6465215

CC1=Cc2c(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)cccc2C1[Zr](Cl)(Cl)(C1C(C)=Cc2c(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)cccc21)[SiH](C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5953025 0.92 RXRA (0.33)
SCHEMBL15809182 0.92
SCHEMBL5837577 0.89 HTR1A (0.34)
SCHEMBL273374 0.89 BRD4 (0.31)
SCHEMBL273761 0.88
SCHEMBL15809188 0.88
SCHEMBL5691737 0.87
SCHEMBL22301297 0.87
SCHEMBL6461111 0.86
SCHEMBL273297 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9988323-B2 Catalyst BOREALIS AG (AT) 2018-06-05 US disclosed
EP-2746301-B1 Catalyst BOREALIS AG (AT) 2018-05-30 EP disclosed
US-9944665-B2 Bridged bis(indenyl) transitional metal complexes, production, and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-04-17 US disclosed
EP-2935295-B1 CATALYST BOREALIS AG (AT) 2018-02-07 EP disclosed
US-20170137343-A1 Catalyst BOREALIS AG (AT) 2017-05-18 US disclosed
US-9598516-B2 Catalyst BOREALIS AG (AT) 2017-03-21 US disclosed
US-9598517-B2 Catalysts BOREALIS AG (AT) 2017-03-21 US disclosed
EP-3083649-A1 BRIDGED BIS(INDENYL) TRANSITIONAL METAL COMPLEXES, PRODUCTION, AND USE THEREOF ExxonMobil Chemical Patents Inc. (US) 2016-10-26 EP disclosed
US-20150344595-A1 CATALYST BOREALIS AG (AT) 2015-12-03 US disclosed
US-20150344596-A1 CATALYSTS BOREALIS AG (AT) 2015-12-03 US disclosed
US-20150183893-A1 Bridged Bis(Indenyl) Transitional Metal Complexes, Production, and Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2015-07-02 US disclosed
WO-2015095188-A1 BRIDGED BIS(INDENYL) TRANSITIONAL METAL COMPLEXES, PRODUCTION, AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-06-25 WO disclosed
EP-2746301-A1 Catalyst Borealis AG (AT) 2014-06-25 EP disclosed
US-6900343-B1 Method for the purification of metallocenes BASELL POLYOLEFINE GMBH (DE) 2005-05-31 US disclosed