Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.46 |
| ▸ | DRD1 | P21728 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6354527 | 0.89 | DRD2 (0.53) | DRD2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6444622 | 0.83 | DRD2 (0.43) | DRD2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4431761 | 0.82 | DRD2 (0.57) | DRD2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11634221 | 0.79 | DRD2 (0.54) | DRD2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11631895 | 0.72 | DRD2 (0.49) | DRD2CHRM2CHRM4CHRM5CHRM1 | |
| Fumaric Acid SCHEMBL11633253 | 0.71 | HRH4 (0.51) | DRD2CHRM2CHRM4CHRM5CHRM1 | |
| Fumaric Acid SCHEMBL11633258 | 0.71 | HRH4 (0.51) | DRD2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4419372 | 0.71 | DRD2 (0.57) | DRD2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4431750 | 0.71 | DRD2 (0.57) | DRD2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11055681 | 0.71 | DRD2 (0.47) | DRD2CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513845-A1 | A PROCESS FOR THE PREPARATION OF OLANZAPINE AND AN INTERMEDIATE THEREFOR | Adamed SP. Z O.O. (PL) | 2005-03-16 | — | — | EP | claimed |
| WO-2004000847-A1 | A PROCESS FOR THE PREPARATION OF OLANZAPINE AND AN INTERMEDIATE THEREFOR | ADAMED SP. Z O.O. (PL) | 2003-12-31 | — | — | WO | claimed |