Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6462075 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6455131 | 0.99 | — | — | |
| Hydrochloric Acid SCHEMBL6453947 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL6465548 | 0.70 | MEN1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL6553639 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL846609 | 0.67 | MEN1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL672606 | 0.66 | FAAH (0.30) | — | |
| Hydrochloric Acid SCHEMBL3931575 | 0.65 | GABRA1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL28357145 | 0.64 | GABRA1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL2777881 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049704-B1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | BASELL POLYOLEFINE GMBH (DE) | 2005-07-27 | — | — | EP | disclosed |
| US-6433203-B1 | COORDINATION POLYMERIZATION CATALYST; ALPHA-OLEFIN POLYMER | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-08-13 | — | — | US | disclosed |
| EP-1049704-A1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | Montell Technology Company bv (NL) | 2000-11-08 | — | — | EP | disclosed |
| WO-2000031088-A1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-06-02 | — | — | WO | disclosed |