SCHEMBL6465664

SCHEMBL6465664

Cc1ccc(S(=O)(=O)NC(=O)Nc2nccs2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.66
KMT2A Q03164 4/20 0.66
MEN1 O00255 3/20 0.66
FBP1 P09467 1/20 0.63
PKM P14618 3/20 0.61
MAPK10 P53779 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
PPIA P62937 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.59
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
ACP1 P24666 1/20 0.58
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
KDM4E B2RXH2 1/20 0.56
LMNA P02545 1/20 0.56
TSHR P16473 1/20 0.55
POLB P06746 1/20 0.54
TP53 P04637 1/20 0.53
CA12 O43570 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8388562 0.81 PPIA (0.76) ALDH1A1KMT2AMEN1PKMNPSR1
SCHEMBL4915214 0.80 SMN1; SMN2 (0.73) ALDH1A1KMT2AMEN1PPIASMN1; SMN2
SCHEMBL9720507 0.80 CA1 (0.60) ALDH1A1KMT2AMEN1FBP1SMN1; SMN2
SCHEMBL957161 0.80 KDM4E (0.59) ALDH1A1KMT2AMEN1FBP1NPC1
SCHEMBL6463108 0.78 LMNA (0.64) ALDH1A1KMT2AMEN1FBP1PKM
SCHEMBL9720508 0.78 CA1 (0.73) ALDH1A1KMT2AMEN1FBP1SMN1; SMN2
SCHEMBL958239 0.77 FBP1 (1.00) KMT2AMEN1FBP1CA1CA2
SCHEMBL31135138 0.77 PPIA (0.56) ALDH1A1KMT2AMEN1PKMMAPK10
SCHEMBL5184740 0.77 LMNA (0.69) ALDH1A1KMT2ANPSR1RAB9ACA1
SCHEMBL13212127 0.76 PTPN1 (0.80) ALDH1A1KMT2AMEN1PKMPPIA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed