Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.73 |
| ▸ | CA2 | P00918 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | FBP1 | P09467 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720507 | 0.80 | CA1 (0.60) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11893082 | 0.79 | ALDH1A1 (0.77) | CA1CA2ALDH1A1LMNA | |
| SCHEMBL6465664 | 0.78 | ALDH1A1 (0.66) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL958239 | 0.77 | FBP1 (1.00) | CA1CA2KMT2AMEN1FBP1 | |
| SCHEMBL957161 | 0.77 | KDM4E (0.59) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL5184740 | 0.77 | LMNA (0.69) | CA1CA2KMT2AALDH1A1RAB9A | |
| SCHEMBL1928662 | 0.76 | CA12 (0.85) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL6243996 | 0.76 | CA12 (0.85) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL956998 | 0.76 | ACP1 (0.65) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL2196247 | 0.75 | AKT1 (0.64) | CA1CA2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087284-A | 5-substituted thiadiazole ureas and their use as herbicides | RHONE-POULENC, INC. (US) | 1992-02-11 | — | — | US | disclosed |
| US-4599424-A | PRE-AND POSTEMERGENCE | RHONE-POULENC, INC. (US) | 1986-07-08 | — | — | US | disclosed |
| US-4182712-A | 5-Substituted thiadiazole ureas | MOBIL OIL CORPORATION (US) | 1980-01-08 | — | — | US | disclosed |
| US-4175081-A | PLANT GROWTH REGULATORS, HERBICIDES | MOBIL OIL CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |