SCHEMBL6465704

SCHEMBL6465704

COc1ccc(S(=O)(=O)NC(=O)NC(=O)NC(=O)NS(=O)(=O)c2ccc(OC)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
MMP1 P03956 1/20 0.61
MMP9 P14780 1/20 0.61
MMP8 P22894 1/20 0.61
MMP13 P45452 1/20 0.61
EGFR P00533 5/20 0.55
CA12 O43570 1/20 0.54
CA9 Q16790 1/20 0.54
CA14 Q9ULX7 1/20 0.54
GFER P55789 1/20 0.54
ERBB2 P04626 4/20 0.54
HSD17B10 Q99714 1/20 0.54
ALDH1A1 P00352 3/20 0.53
GAA P10253 2/20 0.53
KDM4E B2RXH2 1/20 0.53
MAPT P10636 1/20 0.53
FLT1 P17948 1/20 0.52
FLT4 P35916 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19629814 0.86 MMP2 (0.61) MMP2CA1CA2MMP1MMP9
SCHEMBL14342315 0.83 MMP2 (0.57) MMP2CA1CA2MMP1MMP9
SCHEMBL6467327 0.83 ALDH1A1 (0.57) MMP2CA1CA2MMP1MMP9
SCHEMBL26282718 0.82 MMP2 (0.65) MMP2CA1CA2MMP1MMP9
SCHEMBL6102084 0.82 HSD17B10 (0.73) MMP2CA1CA2MMP1MMP9
SCHEMBL7776386 0.82 MMP2 (0.65) MMP2CA1CA2MMP1MMP9
SCHEMBL19630935 0.82 MMP2 (0.56) MMP2CA1CA2MMP1MMP9
SCHEMBL19627375 0.82 HRH3 (0.58) MMP2CA1CA2MMP1MMP9
SCHEMBL6468804 0.81 ALDH1A1 (0.61) MMP2CA1CA2MMP1MMP9
SCHEMBL30620037 0.81 MMP2 (0.62) MMP2CA1CA2MMP1MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-0792755-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-11-11 EP disclosed
EP-0792755-A1 Thermosensitive recording material OJI PAPER COMPANY LIMITED (JP) 1997-09-03 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed