SCHEMBL7776386

SCHEMBL7776386

COc1ccc(S(=O)(=O)NC(=O)O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
MMP1 P03956 1/20 0.65
MMP9 P14780 1/20 0.65
MMP8 P22894 1/20 0.65
MMP13 P45452 1/20 0.65
EGFR P00533 5/20 0.61
ERBB2 P04626 4/20 0.59
CA12 O43570 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
GFER P55789 1/20 0.57
HSD17B10 Q99714 1/20 0.56
FFAR4 Q5NUL3 3/20 0.56
CYTH2 Q99418 1/20 0.55
SLC1A3 P43003 1/20 0.55
SLC1A2 P43004 1/20 0.55
SLC1A1 P43005 1/20 0.55
FLT1 P17948 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4727975 0.95 MMP2 (0.61) MMP2CA1CA2MMP1MMP9
SCHEMBL6102084 0.85 HSD17B10 (0.73) MMP2CA1CA2MMP1MMP9
SCHEMBL26282718 0.85 MMP2 (0.65) MMP2CA1CA2MMP1MMP9
SCHEMBL30620037 0.84 MMP2 (0.62) MMP2CA1CA2MMP1MMP9
SCHEMBL6465704 0.82 MMP2 (0.61) MMP2CA1CA2MMP1MMP9
SCHEMBL19629814 0.82 MMP2 (0.61) MMP2CA1CA2MMP1MMP9
SCHEMBL13751199 0.82 MMP2 (0.56) MMP2CA1CA2MMP1MMP9
SCHEMBL28403383 0.81 EGFR (0.65) MMP2CA1CA2MMP1MMP9
SCHEMBL7892155 0.81 ALDH1A1 (0.66) MMP2CA1CA2MMP1MMP9
SCHEMBL3931514 0.81 MMP2 (0.59) MMP2CA1CA2MMP1MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023177568-A1 CANNABINOID RECEPTOR MODULATING COMPOUNDS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-09-21 WO disclosed
WO-2023114366-A2 SULFONAMIDE DERIVATIVES AND THEIR USE AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2023-06-22 WO disclosed
EP-0832757-B1 REVERSIBLE THERMAL RECORDING MEDIUM OJI PAPER CO (JP) 2001-08-22 EP disclosed
US-5928988-A CONTAINING SULFONYLUREA COLOR DEVELOPER OJI PAPER CO., LTD. (JP) 1999-07-27 US disclosed
EP-0832757-A1 REVERSIBLE THERMAL RECORDING MEDIUM Oji Paper Co., Ltd. (JP) 1998-04-01 EP disclosed