⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446240 | 0.78 | — | — | |
| SCHEMBL9863022 | 0.75 | — | — | |
| SCHEMBL6016861 | 0.75 | — | — | |
| Alcohol SCHEMBL7530022 | 0.74 | TSHR (0.34) | — | |
| SCHEMBL442955 | 0.74 | CHRM1 (0.36) | — | |
| SCHEMBL3797003 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL448883 | 0.71 | FAAH (0.42) | — | |
| SCHEMBL444118 | 0.71 | — | — | |
| Trimethylammonium SCHEMBL11759515 | 0.70 | TSHR (0.48) | — | |
| SCHEMBL5056434 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569651-A1 | TABLET COMPRISING EFLETIRIZINE AND PSEUDOEPHEDRINE | UCB Farchim S.A. (CH) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004052367-A1 | TABLET COMPRISING EFLETIRIZINE AND PSEUDOEPHEDRINE | UCB FARCHIM, S.A. (CH) | 2004-06-24 | — | — | WO | disclosed |
| EP-1157016-A1 | A PROCESS FOR THE PREPARATION OF 2- 2- 4-(DIPHENYLMETHYL)-1-PIPERAZINYL]ETHOXY ACETIC ACID COMPOUNDS OR SALTS THEREOF | A/S GEA Farmaceutisk Fabrik (DK) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000052000-A1 | A PROCESS FOR THE PREPARATION OF 2-{2-[4-(DIPHENYLMETHYL)-1-PIPERAZINYL]ETHOXY}ACETIC ACID COMPOUNDS OR SALTS THEREOF | A/S GEA FARMACEUTISK FABRIK (DK) | 2000-09-08 | — | — | WO | disclosed |