SCHEMBL6466077

SCHEMBL6466077

CC(C)Cc1cc(CC(C)C)c(C(=O)P(=O)(CC(C)CC(C)(C)C)C(=O)c2c(CC(C)C)cc(CC(C)C)cc2CC(C)C)c(CC(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
GFER P55789 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6469388 0.84 GABRA1 (0.41) GABRA1GABRB2MEN1ALDH1A1LMNA
SCHEMBL6465505 0.84 HSPA5 (0.32)
SCHEMBL6466926 0.79 NPC1 (0.33) ALDH1A1HPGD
SCHEMBL6467036 0.77 GABRA1 (0.37) GABRA1GABRB2ALDH1A1
SCHEMBL611535 0.75 L3MBTL1 (0.36) MEN1LMNAHPGDKMT2A
SCHEMBL5997774 0.74 HMGCR (0.32) ALDH1A1HPGD
SCHEMBL6470369 0.73 FABP3 (0.45) GABRA1GABRB2
SCHEMBL125225 0.72 L3MBTL1 (0.34) KMT2A
SCHEMBL14641678 0.72 KDM4E (0.37) MEN1LMNAHPGDKMT2A
SCHEMBL5997227 0.72 LMNA (0.34) GABRA1GABRB2MEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050096406-A1 Reactive diluents and alkyd resin coating compositions PRETOT ROGER (CH) 2005-05-05 US disclosed
US-5534559-A UNSATURATED POLYESTERS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed