Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10571063 | 0.83 | KCNH2 (0.60) | OPRK1SIGMAR1KCNH2 | |
| SCHEMBL2964767 | 0.81 | ADRB2 (0.62) | ADRB2ADRB1LMNAHIF1ASLC6A4 | |
| SCHEMBL7381628 | 0.81 | TMEM97 (0.67) | ADRB2ADRB1SLC6A2OPRK1ALDH1A1 | |
| SCHEMBL11611111 | 0.78 | KCNH2 (0.77) | ADRB2OPRK1SIGMAR1KCNH2 | |
| SCHEMBL4467889 | 0.77 | ADRB2 (0.73) | ADRB2ADRB1LMNAHIF1ASLC6A4 | |
| SCHEMBL9543386 | 0.77 | ADRB2 (0.73) | ADRB2ADRB1LMNAHIF1ASLC6A4 | |
| SCHEMBL4467885 | 0.77 | ADRB2 (0.73) | ADRB2ADRB1LMNAHIF1ASLC6A4 | |
| SCHEMBL10912498 | 0.75 | ADRB2 (0.61) | ADRB2ADRB1LMNAHIF1ASLC6A4 | |
| SCHEMBL11468342 | 0.75 | ADRB2 (0.59) | ADRB2ADRB1LMNAHIF1ASLC6A4 | |
| SCHEMBL11468343 | 0.75 | ADRB2 (0.59) | ADRB2ADRB1LMNAHIF1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597229-A2 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | Applied Research Systems ARS Holding N.V. (AN) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004076407-A2 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2004-09-10 | — | — | WO | disclosed |