Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468342 | 1.00 | ADRB2 (0.59) | ADRB2ADRB1ALDH1A1HIF1ALMNA | |
| Oxalic Acid SCHEMBL11482348 | 0.93 | SMN1; SMN2 (0.54) | ADRB2ADRB1ALDH1A1HIF1ALMNA | |
| SCHEMBL11467406 | 0.92 | ADRB2 (0.61) | ADRB2ADRB1ALDH1A1ADRB3SMN1; SMN2 | |
| SCHEMBL11467407 | 0.92 | ADRB2 (0.61) | ADRB2ADRB1ALDH1A1ADRB3SMN1; SMN2 | |
| Bromide SCHEMBL11470045 | 0.91 | ADRB2 (0.59) | ADRB2ADRB1ALDH1A1ADRB3SMN1; SMN2 | |
| Bromide SCHEMBL11470044 | 0.91 | ADRB2 (0.59) | ADRB2ADRB1ALDH1A1ADRB3SMN1; SMN2 | |
| SCHEMBL10604963 | 0.89 | ADRB2 (0.67) | ADRB2ADRB1ALDH1A1HIF1ALMNA | |
| Acetic Acid SCHEMBL11468057 | 0.86 | SMN1; SMN2 (0.57) | ADRB2ALDH1A1ADRB3SMN1; SMN2TDP1 | |
| SCHEMBL11467451 | 0.85 | ADRB2 (0.54) | ADRB2ADRB1ALDH1A1HIF1ALMNA | |
| SCHEMBL11464952 | 0.85 | LMNA (0.58) | ADRB2ADRB1HIF1ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007716-A1 | R-N-(2-phenyl-2-hydroxyethyl)-3-phenylpropyl amines, their formulations, use and preparation | ELI LILLY AND COMPANY (US) | 1980-02-06 | — | — | EP | claimed |