SCHEMBL6466459

SCHEMBL6466459

CC(C)(C)OC(=O)c1cc(-c2ccc(C(=O)O)c(C(=O)O)c2)ccc1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFD P00746 1/20 0.45
RXRB P28702 2/20 0.44
KDM4E B2RXH2 1/20 0.43
GFER P55789 1/20 0.43
KMT2A Q03164 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
ALDH1A1 P00352 1/20 0.42
MCL1 Q07820 4/20 0.41
RXRA P19793 3/20 0.40
NR1H2 P55055 2/20 0.40
NR1H3 Q13133 2/20 0.40
ACMSD Q8TDX5 3/20 0.40
HNF4A P41235 2/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
DHFR P00374 1/20 0.40
GABRA1 P14867 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27389488 0.85 ALDH1A1 (0.37) KMT2AALDH1A1RXRANR1H2NR1H3
SCHEMBL828860 0.85 ALDH1A1 (0.37) KMT2AALDH1A1RXRANR1H2NR1H3
SCHEMBL828474 0.85 ALDH1A1 (0.37) KMT2AALDH1A1RXRANR1H2NR1H3
SCHEMBL28401369 0.85 ALDH1A1 (0.37) KMT2AALDH1A1RXRANR1H2NR1H3
SCHEMBL17713226 0.83 KDM4E (0.50) KDM4EALDH1A1RXRANR1H2NR1H3
SCHEMBL30638610 0.83 KDM4E (0.50) KDM4EALDH1A1RXRANR1H2NR1H3
SCHEMBL9618204 0.82 ALDH1A1 (0.38) KDM4EKMT2AALDH1A1RXRANR1H2
SCHEMBL436207 0.81 ALDH1A1 (0.51) KDM4EKMT2AALDH1A1MCL1NR1H2
SCHEMBL15920614 0.81 KDM4E (0.47) KDM4E
SCHEMBL20928676 0.81 ALDH1A1 (0.38) RXRBKDM4EALDH1A1RXRANR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0311374-B1 DICYLCOHEXYL-3,4,3'4'-TETRA-CARBOXYLIC ACID OR DIANHYDRIDE THEREOF AND POLYAMIDE-ACID AND POLYMIDE OBTAINED THEREFROM Hitachi Chemical Co., Ltd. (JP) 1992-09-09 EP claimed
US-4958001-A LIQUID CRYSTAL DISPLAY DEVICE HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-09-18 US claimed
EP-0311374-A2 Dicylcohexyl-3,4,3'4'-tetra-carboxylic acid or dianhydride thereof and polyamide-acid and polymide obtained therefrom Hitachi Chemical Co., Ltd. (JP) 1989-04-12 EP claimed
JP-7215912-A None JP disclosed
CN-110818551-B Synthetic method of 3,3',4,4' -biphenyltetracarboxylic acid 常州市阳光药业有限公司 2022-06-24 CN disclosed
CN-113667104-A Hyperbranched polyester and preparation method thereof 扬州帅帅高分子科技有限公司 2021-11-19 CN disclosed
CN-110818551-A Synthetic method of 3,3',4,4' -biphenyltetracarboxylic acid 常州市阳光药业有限公司 2020-02-21 CN disclosed
US-9469621-B2 Method for producing multisubstituted biphenyl compound and solid catalyst to be used therein KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-10-18 US disclosed
US-20150274689-A1 METHOD FOR PRODUCING MULTISUBSTITUTED BIPHENYL COMPOUND AND SOLID CATALYST TO BE USED THEREIN UBE CORPORATION (JP) 2015-10-01 US disclosed
US-6914154-B2 Process for production of biphenyltetracarboxylic acid tetraesters UBE INDUSTRIES, LTD. (JP) 2005-07-05 US disclosed
US-20040039222-A1 Process for production of biphenyltetracarboxylic acid tetraesters UBE INDUSTRIES, LTD. (JP) 2004-02-26 US disclosed
JP-H07215912-A NEW DICYCLOHEXYL-3,4,3',4'-TETRACARBOXYLIC ACID AND ITS PRODUCTION HITACHI CHEM CO LTD 1995-08-15 JP disclosed
US-5216173-A Curing agents for epoxy resins; polyimides HENKEL RESEARCH CORPORATION (US) 1993-06-01 US disclosed
EP-0311374-B1 DICYLCOHEXYL-3,4,3'4'-TETRA-CARBOXYLIC ACID OR DIANHYDRIDE THEREOF AND POLYAMIDE-ACID AND POLYMIDE OBTAINED THEREFROM Hitachi Chemical Co., Ltd. (JP) 1992-09-09 EP disclosed
WO-1991001307-A2 N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF HENKEL RESEARCH CORPORATION (US) 1991-02-07 WO disclosed
US-4958001-A LIQUID CRYSTAL DISPLAY DEVICE HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-09-18 US disclosed
EP-0311374-A2 Dicylcohexyl-3,4,3'4'-tetra-carboxylic acid or dianhydride thereof and polyamide-acid and polymide obtained therefrom Hitachi Chemical Co., Ltd. (JP) 1989-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040039222-A1 Process for production of biphenyltetracarboxylic acid tetraesters PCCA, DDT, DECR2 CFD 1275/4885RXRB 1214/4885KDM4E 3277/4885
US-20150274689-A1 METHOD FOR PRODUCING MULTISUBSTITUTED BIPHENYL COMPOUND AND SOLID CATALYST TO BE USED THEREIN DDT, CYP1A1, CYP1B1 CFD 4502/4885RXRB 1369/4885KDM4E 357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.