Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | DHPS | P49366 | 4/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688137 | 0.93 | KDM4E (0.51) | L3MBTL1DHPSCYP2E1CYP3A4CYP2D6 | |
| SCHEMBL6431729 | 0.84 | NR1H2 (0.51) | L3MBTL1NR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL6427487 | 0.82 | DHPS (0.46) | L3MBTL1DHPSCYP2E1CYP3A4CYP2D6 | |
| SCHEMBL6427000 | 0.75 | NR1H2 (0.60) | L3MBTL1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30875783 | 0.75 | RGS4 (0.60) | L3MBTL1DHPSCYP2E1CYP3A4CYP2D6 | |
| SCHEMBL29259507 | 0.75 | RGS4 (0.60) | L3MBTL1DHPSCYP2E1CYP3A4CYP2D6 | |
| SCHEMBL15437828 | 0.75 | NR1H2 (0.70) | NR1H2NR1H3ALDH1A1MEN1KMT2A | |
| SCHEMBL5049894 | 0.75 | ELANE (0.64) | L3MBTL1KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6426236 | 0.74 | MAPT (0.46) | L3MBTL1NR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL6442280 | 0.74 | MAPT (0.46) | L3MBTL1NR1H2NR1H3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005024755-A2 | MEDICAMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS OR DIABETES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2005-03-17 | — | — | WO | disclosed |