SCHEMBL646662

SCHEMBL646662

OB(O)Oc1ccc(C(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPV6 Q9H1D0 2/20 0.52
ORAI1 Q96D31 1/20 0.52
ORAI2 Q96SN7 1/20 0.52
ORAI3 Q9BRQ5 1/20 0.52
MGLL Q99685 1/20 0.52
KIF11 P52732 3/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 1/20 0.44
TRPV1 Q8NER1 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MAOB P27338 2/20 0.40
AOC3 Q16853 1/20 0.40
TSHR P16473 1/20 0.39
PTGS1 P23219 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29013463 0.98 TRPV6 (0.50) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL7103574 0.98 TRPV6 (0.50) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL30462559 0.94 KIF11 (0.53) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL28321109 0.86 TRPV6 (0.52) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL30448398 0.86 TRPV6 (0.44) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL20787047 0.83 TRPV6 (0.34) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL4442321 0.81 CA1 (0.47) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL3800806 0.80 CA1 (0.38) CA1CA2CA9TSHR
SCHEMBL2410444 0.79 TRPV6 (0.53) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL28146073 0.79 ORAI1 (0.32) TRPV6ORAI1ORAI2ORAI3MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 540 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122038010-A Lubricating grease composition with excellent heat resistance stability, and preparation method and application thereof 思潞博(河南)新材料有限公司 2026-05-15 CN claimed
CN-120115185-A Method for preparing carboxylic ester by catalyzing olefin hydrocarbon esterification through chloralkane reinforced Pd@ polyion liquid 北京理工大学 2025-06-10 CN claimed
CN-120117985-A Method for preparing dicarboxylic acid ester by catalyzing carbonylation of 1, 3-conjugated diene through palladium-dual ligand tandem 北京理工大学 2025-06-10 CN claimed
CN-120033221-A Silicon-based composite material, preparation method thereof and secondary battery 兰溪致德新能源材料有限公司 2025-05-23 CN claimed
CN-119930874-A Supported metallocene catalyst and preparation method and application thereof 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-119930873-A Supported metallocene catalyst and preparation method and application thereof 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-119019229-B Synthesis method of beta-gem difluorophenethyl alcohol or beta-gem difluorophenethyl ether compound and analogues thereof 中国科学技术大学 2025-04-29 CN claimed
CN-119707650-A Functionalized-surface chiral column aromatic hydrocarbon and preparation method and application thereof 宁夏大学 2025-03-28 CN claimed
US-12221499-B2 Catalyst for olefin polymerization and polyolefin prepared using the same Hanwha Solutions Corporation (KR) 2025-02-11 US claimed
CN-119019229-A Synthesis method of beta-gem difluorophenethyl alcohol or beta-gem difluorophenethyl ether compound and analogues thereof 中国科学技术大学 2024-11-26 CN claimed
CN-109496219-A Utilize the high working property high density ethylene quasi polymer and preparation method thereof of composite load type metallocene catalyst 韩华化学株式会社 2019-03-19 CN claimed
CN-109476776-A Composite catalyst composition, preparation method and the polyolefin using its preparation 韩华石油化学株式会社 2019-03-15 CN claimed
CN-109415450-A Support type mixes metallocene catalyst and the polyolefin resin outstanding using its processability 韩华化学株式会社 2019-03-01 CN claimed
CN-109415451-A Mix the high density ethylene quasi polymer and preparation method thereof of metallocene catalyst using support type 韩华化学株式会社 2019-03-01 CN claimed
CN-104804045-B Near-infrared light-emitting material and organic electroluminescence device 清华大学 2018-04-10 CN claimed
CN-104804045-A Near-infrared luminous material and OLEDs (organic light-emitting diodes) UNIV TSINGHUA 2015-07-29 CN claimed
CN-101052660-B Polymerization catalyst for conjugated diene polymer, process for producing conjugated diene polymer using the same, rubber composition for tire, and rubber composition for golf ball UBE INDUSTRIES 2010-07-14 CN claimed
EP-1167422-B1 PROCESS OF PREPARING CONDENSED POLYMERS WITH POLYCARBOXYLIC ACIDS AND POLYAMINES JAPAN SCIENCE & TECH AGENCY (JP) 2005-06-01 EP claimed
US-6586555-B1 To produce polyamides, polyimides, and/or polyamideimides JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-07-01 US claimed
EP-1167422-A1 PROCESS FOR PRODUCING POLYCONDENSATE FROM POLYCARBOXYLIC ACID AND POLYAMINE Japan Science and Technology Corporation (JP) 2002-01-02 EP claimed