SCHEMBL7103574

SCHEMBL7103574

OB(O)Oc1ccc(C(F)(F)F)cc1.[NaH]

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPV6 Q9H1D0 2/20 0.50
ORAI1 Q96D31 1/20 0.50
ORAI2 Q96SN7 1/20 0.50
ORAI3 Q9BRQ5 1/20 0.50
MGLL Q99685 1/20 0.50
KIF11 P52732 3/20 0.43
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 1/20 0.42
TRPV1 Q8NER1 1/20 0.41
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
ALDH1A1 P00352 2/20 0.40
MAOB P27338 2/20 0.39
AOC3 Q16853 1/20 0.39
PTGS1 P23219 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL646662 0.98 TRPV6 (0.52) TRPV6ORAI1ORAI2ORAI3MGLL
Ammonia Solution, Strong SCHEMBL29013463 0.96 TRPV6 (0.50) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL30462559 0.92 KIF11 (0.53) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL28321109 0.84 TRPV6 (0.52) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL30448398 0.84 TRPV6 (0.44) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL20787047 0.81 TRPV6 (0.34) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL4442321 0.79 CA1 (0.47) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL646926 0.78 CES2 (0.40) TRPV6ORAI1ORAI2ORAI3MGLL
SCHEMBL3800806 0.78 CA1 (0.38) CA1CA2CA9TSHR
SCHEMBL2410444 0.78 TRPV6 (0.53) TRPV6ORAI1ORAI2ORAI3MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114544730-B Ion sensor and preparation method and application thereof 华南农业大学 2023-09-15 CN claimed
EP-1006119-B1 NOVEL CRYSTALLINE ION-ASSOCIATION SUBSTANCE, PROCESS FOR PRODUCING THE SAME, AND LATENT PHOTOPOLYMERIZATION INITIATOR AUTEX INC (JP) 2003-09-03 EP disclosed