Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803543 | 0.75 | ALDH1A1 (0.62) | ALDH1A1 | |
| SCHEMBL7759159 | 0.75 | — | — | |
| SCHEMBL2220993 | 0.75 | ALDH1A1 (0.62) | ALDH1A1 | |
| SCHEMBL10950356 | 0.71 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL10936087 | 0.71 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL11820966 | 0.71 | — | — | |
| SCHEMBL2116285 | 0.71 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL13928058 | 0.70 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL16541056 | 0.70 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL8277381 | 0.70 | ALDH1A1 (0.54) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113409-A1 | Method for the prevention or treatment of pain, inflammation and inflammation-related disorders with a Cox-2 selective inhibitor in combination with a nitric oxide-donating agent and compositions therewith | PHARMACIA CORPORATION (US) | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113409-A1 | Method for the prevention or treatment of pain, inflammation and inflammation-related disorders with a Cox-2 selective inhibitor in combination with a nitric oxide-donating agent and compositions therewith | PTGS2, NOS2, PTGES2 | ALDH1A1 574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.