SCHEMBL6466795

SCHEMBL6466795

Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc(NC(=O)NS(=O)(=O)c3ccc(C)cc3)c(C)c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.67
MEN1 O00255 2/20 0.67
CA12 O43570 3/20 0.64
CA9 Q16790 3/20 0.64
CA1 P00915 2/20 0.64
CA2 P00918 2/20 0.64
CA4 P22748 2/20 0.64
CA6 P23280 2/20 0.64
CA5A P35218 2/20 0.64
CA7 P43166 2/20 0.64
CA13 Q8N1Q1 2/20 0.64
CA14 Q9ULX7 2/20 0.64
TP53 P04637 1/20 0.64
LMNA P02545 3/20 0.63
ALDH1A1 P00352 2/20 0.61
PPARG P37231 1/20 0.61
RAB9A P51151 1/20 0.61
RXFP1 Q9HBX9 1/20 0.61
NR2E3 Q9Y5X4 1/20 0.61
NCOR2 Q9Y618 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6466462 0.89 KMT2A (0.67) KMT2AMEN1CA12CA9CA1
SCHEMBL12530476 0.89 KMT2A (0.71) KMT2AMEN1CA12CA9CA1
SCHEMBL6464678 0.87 LMNA (0.63) KMT2AMEN1CA12CA9CA1
SCHEMBL6468156 0.87 ALDH1A1 (0.69) KMT2AMEN1CA12CA9CA1
SCHEMBL24691473 0.86 KMT2A (0.62) KMT2AMEN1CA12CA9CA1
SCHEMBL1928662 0.85 CA12 (0.85) KMT2AMEN1CA12CA9CA1
SCHEMBL6243996 0.85 CA12 (0.85) KMT2AMEN1CA12CA9CA1
SCHEMBL9486532 0.85 CA12 (0.67) KMT2AMEN1CA12CA9CA1
SCHEMBL6466852 0.84 ALDH1A1 (0.66) KMT2AMEN1CA12CA9CA1
SCHEMBL8418160 0.84 KMT2A (0.64) KMT2AMEN1CA12CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
US-5990353-A DEMETALLIZING AN ARYLSULFONAMIDE ALKALI METAL SALT WITH AN AROMATIC ISOCYANATE COMPOUND IN AT LEAST ONE SOLVENT; USE AS A COLOR DEVELOPER FOR A THERMAL RECORDING MATERIAL WITH IMPROVED OIL RESISTANCE AND NONPLASTICIZED YAMAMOTO CHEMICALS, INC. (JP) 1999-11-23 US disclosed
EP-0879816-A1 Process for producing arylsulfonylureide compounds Yamamoto Chemicals, Inc. (JP) 1998-11-25 EP disclosed