SCHEMBL6468156

SCHEMBL6468156

Cc1ccc(S(=O)(=O)NC(=O)Nc2cc(C)c(NC(=O)NS(=O)(=O)c3ccc(C)cc3)cc2C)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.69
LMNA P02545 3/20 0.69
TSHR P16473 1/20 0.69
KMT2A Q03164 2/20 0.66
L3MBTL1 Q9Y468 1/20 0.65
GAA P10253 3/20 0.61
KDM4E B2RXH2 2/20 0.61
MAPT P10636 1/20 0.61
NLRP3 Q96P20 2/20 0.60
TP53 P04637 1/20 0.60
CA12 O43570 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
CA4 P22748 1/20 0.60
CA6 P23280 1/20 0.60
CA5A P35218 1/20 0.60
CA7 P43166 1/20 0.60
CA9 Q16790 1/20 0.60
CA13 Q8N1Q1 1/20 0.60
CA14 Q9ULX7 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8415208 0.90 LMNA (0.59) ALDH1A1LMNATSHRKMT2AL3MBTL1
SCHEMBL6464678 0.88 LMNA (0.63) ALDH1A1LMNATSHRKMT2AL3MBTL1
SCHEMBL6466462 0.87 KMT2A (0.67) ALDH1A1LMNATSHRKMT2AL3MBTL1
SCHEMBL6466795 0.87 KMT2A (0.67) ALDH1A1LMNATSHRKMT2AL3MBTL1
SCHEMBL24691473 0.87 KMT2A (0.62) ALDH1A1LMNATSHRKMT2AL3MBTL1
SCHEMBL8724554 0.85 L3MBTL1 (0.81) ALDH1A1LMNATSHRKMT2AL3MBTL1
SCHEMBL6466518 0.85 LMNA (0.56) ALDH1A1LMNATSHRKMT2AL3MBTL1
SCHEMBL6466852 0.84 ALDH1A1 (0.66) ALDH1A1LMNATSHRKMT2AL3MBTL1
SCHEMBL6465678 0.84 ALDH1A1 (0.59) ALDH1A1LMNATSHRKMT2AL3MBTL1
SCHEMBL5185904 0.84 L3MBTL1 (0.74) ALDH1A1LMNATSHRKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-0738610-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-17 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0738610-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1996-10-23 EP disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed