Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693948 | 0.86 | FDPS (0.69) | FDPSALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL6463807 | 0.85 | FDPS (0.53) | FDPSALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL19164508 | 0.83 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL10931446 | 0.81 | MAOA (0.43) | SMN1; SMN2LMNAMAPTTSHRPOLB | |
| SCHEMBL941493 | 0.80 | MAPT (0.50) | ALDH1A1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL28437357 | 0.80 | FDPS (0.63) | FDPSALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL11058632 | 0.80 | GLA (0.60) | ALDH1A1SMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL11068199 | 0.80 | GLA (0.60) | ALDH1A1SMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL11663187 | 0.78 | ALDH1A1 (0.64) | FDPSALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL19771207 | 0.78 | FDPS (0.57) | FDPSALDH1A1SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594860-A2 | LIBRARY OF BIPHENYL DERIVATIVES USEFUL FOR IDENTIFYING COMPOUNDS HAVING BOTH BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | Theravance Inc (US) | 2005-11-16 | — | — | EP | disclosed |
| US-20050112182-A1 | Medical adhesive and medical covering agent using ultraviolet ray curable chitosan derivative | NITTO DENKO CORPORATION (33)% (JP) | 2005-05-26 | — | — | US | disclosed |
| WO-2004074812-A2 | LIBRARY OF BIPHENYL DERIVATIVES USEFUL FOR IDENTIFYING COMPOUNDS HAVING BOTH BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | THERAVANCE INC (US) | 2004-09-02 | — | — | WO | disclosed |
| JP-2000109501-A | PRODUCTION OF N-ALKYLCHITOSAN DERIVATIVE, N- ALKYLCHITOSAN DERIVATIVE AND POLYMER USING THE SAME | DAISHIN KAGAKU KK | 2000-04-18 | — | — | JP | disclosed |
| US-4444868-A | CONTAINING STYRYL-TYPE NITROGEN-HETEROCYCLE RESIDUE POLYMER AND ACID | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1984-04-24 | — | — | US | disclosed |