Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6462287 | 0.88 | FAAH (0.44) | POLBGAAFAAHCES1DAGLA | |
| SCHEMBL7042871 | 0.83 | PTPN1 (0.43) | PTPN1PTPN2EPHX2 | |
| SCHEMBL6463429 | 0.81 | DAGLA (0.47) | PTPN1POLBGAAFAAHCES1 | |
| SCHEMBL6466336 | 0.81 | MEN1 (0.40) | FAAHCES1DAGLAEPHX2 | |
| SCHEMBL6473321 | 0.80 | MEN1 (0.40) | FAAHCES1DAGLAEPHX2 | |
| SCHEMBL6463649 | 0.80 | MEN1 (0.40) | FAAHCES1DAGLAEPHX2 | |
| SCHEMBL6462563 | 0.79 | KDM4E (0.43) | PTPN1CNR2 | |
| SCHEMBL5731227 | 0.76 | CTSK (0.46) | XDHEPHX2 | |
| SCHEMBL5731226 | 0.76 | CTSK (0.46) | XDHEPHX2 | |
| Hydrochloric Acid SCHEMBL6466455 | 0.75 | SMN1; SMN2 (0.36) | POLBFAAHCES1DAGLAXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |