Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 4/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473321 | 1.00 | MEN1 (0.40) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL6466336 | 0.99 | MEN1 (0.40) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL6465745 | 0.90 | KMT2A (0.43) | MEN1KMT2ARAB9ALMNACTSL | |
| SCHEMBL6465251 | 0.90 | LMNA (0.40) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL7186564 | 0.88 | MMP1 (0.39) | MEN1KMT2ARAB9ACTSLCTSB | |
| SCHEMBL7042906 | 0.87 | DAGLA (0.46) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL7047598 | 0.87 | CTSL (0.40) | KMT2ALMNAMAPTCTSLCTSS | |
| SCHEMBL6462287 | 0.86 | FAAH (0.44) | RAB9ALMNAMAPTHPGDFAAH | |
| SCHEMBL6466278 | 0.85 | BMP1 (0.36) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL7047934 | 0.85 | CTSS (0.46) | CTSLCTSBCTSSMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |