SCHEMBL6467495

SCHEMBL6467495

CS(=O)(=O)NC(=O)Nc1cccc(NC(=O)NS(C)(=O)=O)c1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 2/20 0.52
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
ALDH1A1 P00352 3/20 0.50
DDX3X O00571 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MAPT P10636 4/20 0.48
LMNA P02545 2/20 0.48
HTT P42858 1/20 0.48
USP2 O75604 1/20 0.48
TP53 P04637 1/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
SIRT1 Q96EB6 1/20 0.47
MGLL Q99685 1/20 0.47
GPR35 Q9HC97 1/20 0.47
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4202296 0.86 ACP1 (0.69) ACP1KMT2ASMN1; SMN2MAPTLMNA
SCHEMBL29162150 0.84 TSHR (0.49) MEN1KMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL11324602 0.83 GPR35 (0.55) MEN1KMT2AALDH1A1DDX3XSMN1; SMN2
SCHEMBL15093883 0.80 KCNK3 (0.68) MEN1KMT2AMAPTLMNAHTT
SCHEMBL8867229 0.80 MAOB (0.42) ACP1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL8867221 0.80 MAOB (0.42) ACP1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL8867234 0.80 MAOB (0.42) ACP1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL14365821 0.79 ALDH1A1 (0.61) MEN1KMT2AALDH1A1DDX3XSMN1; SMN2
SCHEMBL23486690 0.77 CA12 (0.59) MEN1KMT2AALDH1A1MAPTLMNA
SCHEMBL6241750 0.76 LMNA (0.80) MEN1KMT2AALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-0604832-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed