SCHEMBL6468006

SCHEMBL6468006

Cc1c(C=O)cccc1OOc1cccc(C=O)c1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.55
TLR2 O60603 1/20 0.55
TLR1 Q15399 1/20 0.55
TLR6 Q9Y2C9 1/20 0.55
ALDH1A1 P00352 7/20 0.52
LMNA P02545 3/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
HPGD P15428 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TSHR P16473 2/20 0.46
SRC P12931 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954368 0.87 ERN1 (0.66) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL738533 0.87 ERN1 (0.66) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL1959471 0.84 ERN1 (0.53) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL4358123 0.83 ALDH1A1 (0.46) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL2451551 0.81 ALDH1A1 (0.59) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL20818485 0.80 ALDH1A1 (0.50) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL2390071 0.79 ERN1 (0.56) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL17073482 0.79 ALDH1A1 (0.48) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL30331767 0.79 ERN1 (0.56) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL19911767 0.79 ERN1 (0.56) ERN1TLR2TLR1TLR6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6951904-B1 Process for increasing the melt strength of polypropylene POLYMERS AUSTRALIA PTY LIMITED (AU) 2005-10-04 US claimed
EP-1080148-A4 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LTD (AU) 2003-02-05 EP claimed
EP-1080148-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE Polymers Australia PTY Limited (AU) 2001-03-07 EP claimed
WO-1999036466-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LIMITED (AU) 1999-07-22 WO claimed
US-6951904-B1 Process for increasing the melt strength of polypropylene POLYMERS AUSTRALIA PTY LIMITED (AU) 2005-10-04 US disclosed
EP-1080148-A4 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LTD (AU) 2003-02-05 EP disclosed
EP-1080148-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE Polymers Australia PTY Limited (AU) 2001-03-07 EP disclosed
WO-1999036466-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LIMITED (AU) 1999-07-22 WO disclosed