SCHEMBL738533

SCHEMBL738533

COc1cccc(C=O)c1C

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 3/20 0.66
TLR2 O60603 1/20 0.66
TLR1 Q15399 1/20 0.66
TLR6 Q9Y2C9 1/20 0.66
SRC P12931 1/20 0.54
ALDH1A1 P00352 6/20 0.52
LMNA P02545 3/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
KDM4E B2RXH2 1/20 0.48
HPGD P15428 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46
NFE2L2 Q16236 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954368 1.00 ERN1 (0.66) ERN1TLR2TLR1TLR6SRC
SCHEMBL19911767 0.91 ERN1 (0.56) ERN1TLR2TLR1TLR6SRC
SCHEMBL6468006 0.87 ERN1 (0.55) ERN1TLR2TLR1TLR6SRC
SCHEMBL13140330 0.84 ERN1 (0.49) ERN1TLR2TLR1TLR6SRC
SCHEMBL30203585 0.83 ERN1 (0.66) ERN1TLR2TLR1TLR6SRC
SCHEMBL851964 0.83 ALDH1A1 (0.52) ERN1TLR2TLR1TLR6SRC
SCHEMBL29953692 0.83 ALDH1A1 (0.52) ERN1TLR2TLR1TLR6SRC
2-Methoxybenzaldehyde SCHEMBL8469378 0.82 ALDH1A1 (0.66) ERN1TLR2TLR1TLR6SRC
SCHEMBL31689790 0.82 NFE2L2 (0.55) ERN1TLR2TLR1TLR6CYP1A2
SCHEMBL31689795 0.82 NFE2L2 (0.55) ERN1TLR2TLR1TLR6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4624447-A1 METHODS OF MAKING AND USING 1-METHYLEFFUSOL Laboratory for Synthetic Chemistry and Chemical Biology Limited (HK) 2025-10-01 EP claimed
CN-118955434-A Modified multi-functionality epoxy resin and preparation method and application thereof 韦尔通科技股份有限公司 2024-11-15 CN claimed
CN-118956309-A Underfill adhesive, and preparation method and application thereof 韦尔通科技股份有限公司 2024-11-15 CN claimed
CN-115335378-A Monoacylglycerol lipase modulators 詹森药业有限公司 2022-11-11 CN claimed
EP-3131539-B1 SEMICARBAZIDE-SENSITIVE AMINE OXIDASE INHIBITORS FOR USE AS ANALGESICS IN TRAUMATIC NEUROPATHY AND NEUROGENIC INFLAMMATION PECSI TUDOMANYEGYETEM (HU) 2018-12-05 EP claimed
EP-0639559-B1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM & HAAS (US) 1997-10-15 EP claimed
EP-4624447-A1 METHODS OF MAKING AND USING 1-METHYLEFFUSOL Laboratory for Synthetic Chemistry and Chemical Biology Limited (HK) 2025-10-01 EP disclosed
US-20250115577-A1 BCL-2 Inhibitors Eil Therapeutics, Inc. 2025-04-10 US disclosed
CN-115335378-B Monoacylglycerol lipase modulators 詹森药业有限公司 2025-03-04 CN disclosed
CN-118955434-A Modified multi-functionality epoxy resin and preparation method and application thereof 韦尔通科技股份有限公司 2024-11-15 CN disclosed
CN-118956309-A Underfill adhesive, and preparation method and application thereof 韦尔通科技股份有限公司 2024-11-15 CN disclosed
EP-4457223-A1 BCL-2 INHIBITORS Eil Therapeutics, Inc. (US) 2024-11-06 EP disclosed
CN-118451070-A BCL-2 inhibitors 伊尔治疗学股份有限公司 2024-08-06 CN disclosed
EP-0639559-A1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM AND HAAS COMPANY (US) 1995-02-22 EP disclosed
US-5225584-A Phosphonate esters and trialkylsilyl phosphonate esters TROPIX, INC. (US) 1993-07-06 US disclosed
EP-0441948-A4 SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR 1992-06-03 EP disclosed
EP-0441948-A1 SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR TROPIX, INC. (US) 1991-08-21 EP disclosed
WO-1991003479-A1 SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR TROPIX, INC. (US) 1991-03-21 WO disclosed
US-4444567-A ALKOXY BENZALDEHYDES, ALKOXY BENZOATES PHILLIPS PETROLEUM COMPANY (US) 1984-04-24 US disclosed
US-4058642-A HYPERTENSIVE BOEHRINGER INGELHEIM GMBH (DT) 1977-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115577-A1 BCL-2 Inhibitors BCL2, BCL2L1, BCL2L2 ERN1 1457/4885TLR2 3820/4885TLR1 4564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.