Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MDH2 | P40926 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468103 | 0.82 | CTSA (0.41) | MAPTTSHRTDP1ADORA2AADORA1 | |
| SCHEMBL2709818 | 0.81 | ADORA2A (0.39) | MAPTTDP1ADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL2710671 | 0.78 | ADORA2A (0.37) | TDP1ADORA2AADORA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9277021 | 0.70 | TSHR (0.71) | ESR1L3MBTL1TSHRTDP1CYP1A2 | |
| SCHEMBL23250562 | 0.69 | ESR1 (0.67) | ESR1L3MBTL1TSHRTDP1CNR2 | |
| SCHEMBL28388797 | 0.69 | ALDH1A1 (0.65) | MAPTL3MBTL1TSHRTDP1SMN1; SMN2 | |
| SCHEMBL4525162 | 0.68 | PDK2 (0.41) | MAPTL3MBTL1TSHRTDP1CYP1A2 | |
| SCHEMBL14919190 | 0.67 | L3MBTL1 (0.55) | ESR1L3MBTL1TSHRTDP1CYP1A2 | |
| SCHEMBL2347995 | 0.67 | ESR2 (0.46) | L3MBTL1TSHRADORA2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6057190 | 0.67 | HPGD (0.60) | ESR1L3MBTL1TSHRTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |