Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 8/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6462866 | 0.93 | FAAH (0.38) | FAAHCES1DAGLAXDHHSF1 | |
| SCHEMBL6461829 | 0.88 | CTSS (0.43) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL7045520 | 0.85 | FAAH (0.36) | FAAHCES1DAGLACTSSCYP3A4 | |
| SCHEMBL6463182 | 0.85 | CTSS (0.43) | FAAHCES1CTSSCYP3A4CYP2C9 | |
| SCHEMBL7046391 | 0.84 | FAAH (0.37) | FAAHCES1DAGLAXDHALDH1A1 | |
| SCHEMBL6468151 | 0.84 | FAAH (0.36) | FAAHCES1XDHHSF1CTSS | |
| SCHEMBL7049518 | 0.83 | DAGLA (0.46) | FAAHCES1DAGLAXDHALDH1A1 | |
| SCHEMBL7043169 | 0.82 | CTSS (0.44) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL7043202 | 0.81 | P2RY14 (0.37) | FAAHCES1XDHHSF1CYP3A4 | |
| SCHEMBL6466564 | 0.80 | DAGLA (0.41) | FAAHCES1DAGLAALDH1A1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |