Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 7/20 | 0.38 |
| ▸ | EDNRB | P24530 | 3/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643780 | 0.89 | CYP1A2 (0.39) | EDNRAEDNRBLMNA | |
| SCHEMBL13309259 | 0.86 | CYP1A2 (0.38) | EDNRAEDNRBLMNA | |
| SCHEMBL643824 | 0.85 | CYP1A2 (0.38) | EDNRAEDNRBLMNA | |
| SCHEMBL644184 | 0.84 | CYP1A2 (0.45) | EDNRAEDNRBLMNA | |
| SCHEMBL646932 | 0.82 | CYP1A2 (0.41) | EDNRAEDNRBLMNA | |
| SCHEMBL6493816 | 0.79 | MCHR1 (0.41) | EDNRAEDNRBFPR1FPR2 | |
| SCHEMBL644257 | 0.78 | KIF11 (0.45) | — | |
| SCHEMBL644186 | 0.77 | KCNH2 (0.35) | EDNRAEDNRBLMNA | |
| SCHEMBL6479580 | 0.76 | GSK3A (0.39) | LMNA | |
| SCHEMBL644775 | 0.76 | KCNH2 (0.39) | FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050165089-A1 | Compounds, compositions and methods | CYTOKINETICS, INCORPORATED | 2005-07-28 | — | — | US | claimed |
| US-20050165089-A1 | Compounds, compositions and methods | CYTOKINETICS, INCORPORATED | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165089-A1 | Compounds, compositions and methods | ALPP, PCNA, MKI67 | EDNRA 2546/4885EDNRB 2104/4885FPR1 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.