Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 2/20 | 0.40 |
| ▸ | EDNRA | P25101 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13309259 | 0.84 | CYP1A2 (0.38) | EDNRBEDNRACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL643780 | 0.82 | CYP1A2 (0.39) | KCNH2EDNRBEDNRACYP1A2CYP3A4 | |
| SCHEMBL643824 | 0.80 | CYP1A2 (0.38) | MCHR1KCNH2EDNRBEDNRACYP1A2 | |
| SCHEMBL6468495 | 0.79 | EDNRA (0.38) | EDNRBEDNRAFPR1FPR2 | |
| SCHEMBL644184 | 0.79 | CYP1A2 (0.45) | MCHR1KCNH2EDNRBEDNRACYP1A2 | |
| SCHEMBL6493822 | 0.79 | PRKDC (0.35) | MCHR1KCNH2PRKDCACHE | |
| SCHEMBL646932 | 0.77 | CYP1A2 (0.41) | MCHR1KCNH2EDNRBEDNRACYP1A2 | |
| SCHEMBL644186 | 0.71 | KCNH2 (0.35) | MCHR1KCNH2EDNRBEDNRACYP3A4 | |
| SCHEMBL644257 | 0.70 | KIF11 (0.45) | KCNH2PRKDCALDH1A1ACHE | |
| SCHEMBL644775 | 0.70 | KCNH2 (0.39) | MCHR1KCNH2PRKDCALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924376-B2 | Compounds, compositions and methods | CYTOKINETICS, INC. (US) | 2005-08-02 | — | — | US | disclosed |
| US-20040082638-A1 | Compounds, compositions and methods | CYTOKINETICS, INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082638-A1 | Compounds, compositions and methods | ALPP, PCNA, MKI67 | MCHR1 4421/4885KCNH2 2582/4885EDNRB 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.