Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 4/20 | 0.52 |
| ▸ | CES1 | P23141 | 4/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759908 | 0.98 | KMT2A (0.64) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL2560516 | 0.98 | KMT2A (0.64) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL20943425 | 0.98 | KMT2A (0.64) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL12500924 | 0.98 | KMT2A (0.64) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL1412994 | 0.98 | KMT2A (0.64) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL117081 | 0.98 | KMT2A (0.64) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL116979 | 0.98 | KMT2A (0.64) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL951860 | 0.98 | KMT2A (0.64) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL12500927 | 0.98 | KMT2A (0.64) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL6467413 | 0.98 | KMT2A (0.64) | KMT2AMAPTCES2CES1HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| CN-114409680-B | PPAR agonists and uses thereof | 上海怡立舍生物技术有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-108250058-B | PPAR agonists and their use in the treatment of Alzheimer's disease and other diseases | 上海怡立舍生物技术有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-109212066-A | The measuring method of non-fat class organic acid in a kind of tobacco and tobacco product | 中国烟草总公司郑州烟草研究院 | 2019-01-15 | — | — | CN | disclosed |
| CN-108368265-A | Thiadiazoles and pyridine polymers, its synthesis and application thereof | 默克专利股份有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-108148073-A | Organic semiconductor compound | 默克专利股份有限公司 | 2018-06-12 | — | — | CN | disclosed |
| CN-105658761-B | Conjugated polymer | 默克专利股份有限公司 | 2018-04-24 | — | — | CN | disclosed |
| CN-107922369-A | Compound for optical activity device | 默克专利股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107915661-A | Organic semiconductor compound | 默克专利股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107636040-A | Thiadiazolopyridine Polymers, Their Synthesis And Their Use | 默克专利股份有限公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-106536528-A | Polycyclic polymers based on tetra-heteroaryl indacenodithiophenes and their use | 默克专利股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| US-20130165446-A1 | BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE | HORIKOSHI, HIROYOSHI (CA) | 2013-06-27 | — | — | US | disclosed |
| EP-2581373-A1 | BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE | Fujita, Takashi (JP) | 2013-04-17 | — | — | EP | disclosed |
| CN-102026965-A | Method for producing isocyanate | ASAHI CHEMICAL CORP (JP) | 2011-04-20 | — | — | CN | disclosed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | disclosed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |
| EP-0751133-B1 | Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same | MITSUI CHEMICALS INC (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5770108-A | HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0751133-A1 | Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1997-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | IL4, ARG2, CASP4 | KMT2A 3219/4885MAPT 1906/4885CES2 1232/4885 |
| US-20130165446-A1 | BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE | PPARG, PPARA, PPARD | KMT2A 1996/4885MAPT 4753/4885CES2 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.