Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | GART | P22102 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6465933 | 0.99 | ALDH1A1 (0.38) | ALDH1A1CTSCPTPN1PTPN2FAAH | |
| SCHEMBL6695960 | 0.92 | PTPN1 (0.38) | ALDH1A1CTSCPTPN1PTPN2CTSB | |
| SCHEMBL6702111 | 0.92 | PTPN1 (0.38) | ALDH1A1CTSCPTPN1PTPN2CTSB | |
| SCHEMBL6702107 | 0.92 | PTPN1 (0.38) | ALDH1A1CTSCPTPN1PTPN2CTSB | |
| SCHEMBL6695966 | 0.92 | PTPN1 (0.38) | ALDH1A1CTSCPTPN1PTPN2CTSB | |
| SCHEMBL6630202 | 0.92 | PTPN1 (0.38) | ALDH1A1CTSCPTPN1PTPN2CTSB | |
| SCHEMBL6632738 | 0.92 | PTPN1 (0.38) | ALDH1A1CTSCPTPN1PTPN2CTSB | |
| SCHEMBL5946157 | 0.90 | ALDH1A1 (0.39) | ALDH1A1CTSCPTPN1PTPN2 | |
| Hydrochloric Acid SCHEMBL5946146 | 0.89 | ALDH1A1 (0.39) | ALDH1A1CTSCPTPN1PTPN2 | |
| Hydrochloric Acid SCHEMBL5946155 | 0.89 | ALDH1A1 (0.39) | ALDH1A1CTSCPTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | disclosed |
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | SERPINB1, CTRL, CTSZ | ALDH1A1 3027/4885CTSC 7/4885PTPN1 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.