SCHEMBL6468790

SCHEMBL6468790

CS(=O)(=O)N(S)C(=O)Nc1cccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.53
GAA P10253 2/20 0.53
KEAP1 Q14145 1/20 0.51
RAB9A P51151 5/20 0.49
CYP1A2 P05177 3/20 0.49
NPC1 O15118 3/20 0.49
CYP2C19 P33261 2/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
ALDH1A1 P00352 4/20 0.48
HPGD P15428 2/20 0.48
MAPT P10636 3/20 0.48
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
TDP1 Q9NUW8 1/20 0.47
NOX1 Q9Y5S8 1/20 0.47
EPHX1 P07099 1/20 0.47
HSD17B10 Q99714 1/20 0.46
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11641269 0.78 KDM4E (0.62) KDM4EGAARAB9ACYP1A2NPC1
SCHEMBL11437293 0.74 KDM4E (0.57) KDM4EGAARAB9ACYP1A2NPC1
SCHEMBL6537093 0.74 NLRP3 (0.61) KDM4EGAAKEAP1RAB9ACYP1A2
SCHEMBL14859449 0.72 RAB9A (0.56) KDM4EGAARAB9ACYP1A2NPC1
SCHEMBL28700566 0.72 KEAP1 (0.67) KDM4EGAAKEAP1RAB9ACYP1A2
SCHEMBL5932951 0.72 KDM4E (0.69) KDM4EGAARAB9ACYP1A2NPC1
SCHEMBL357522 0.72 KDM4E (0.69) KDM4EGAARAB9ACYP1A2NPC1
SCHEMBL29514721 0.72 KDM4E (0.69) KDM4EGAARAB9ACYP1A2NPC1
SCHEMBL9547527 0.72 KDM4E (0.59) KDM4EGAARAB9ACYP1A2NPC1
SCHEMBL13984133 0.72 EPHX1 (0.58) KDM4EGAARAB9ACYP1A2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5449657-A Sulfonyl (thio)ureas NEW OJI PAPER CO., LTD. (JP) 1995-09-12 US claimed
EP-0615859-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-09-21 EP claimed
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
US-6740465-B2 MULTILAYER; TRANSPARENT SUPPORT; HEAT SENSITIVE ELEMENT AND RELEASE AGENT SIPIX IMAGING, INC. 2004-05-25 US disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-1289768-A2 IMAGING MEDIA CONTAINING HEAT DEVELOPABLE PHOTOSENSITIVE MICROCAPSULES Sipix Imaging, Inc. (US) 2003-03-12 EP disclosed
CN-1386095-A Imaging media containing heat developable photosensitive microcapsule SIPIX IMAGING INC (US) 2002-12-18 CN disclosed
US-20020155372-A1 Imaging media containing heat developable photosensitive microcapsules SIPIX IMAGING, INC. 2002-10-24 US disclosed
WO-2001092024-A2 IMAGING MEDIA CONTAINING HEAT DEVELOPABLE PHOTOSENSITIVE MICROCAPSULES SIPIX IMAGING, INC. (US) 2001-12-06 WO disclosed
EP-0615859-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
US-5449657-A Sulfonyl (thio)ureas NEW OJI PAPER CO., LTD. (JP) 1995-09-12 US disclosed
EP-0615859-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-09-21 EP disclosed