Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1540060 | 1.00 | HSD17B10 (0.48) | HSD17B10POLBSIGMAR1FKBP1ABCL2L1 | |
| SCHEMBL1541034 | 0.88 | LTA4H (0.50) | SIGMAR1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL1539950 | 0.87 | ACHE (0.50) | POLBSIGMAR1KDM4EACHEKMT2A | |
| SCHEMBL1539920 | 0.87 | POLB (0.60) | POLBFKBP1ARAB9ASMN1; SMN2 | |
| SCHEMBL1540278 | 0.87 | HSD17B10 (0.51) | HSD17B10BCL2L1KDM4ENPC1RAB9A | |
| SCHEMBL1540208 | 0.85 | SIGMAR1 (0.44) | SIGMAR1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL1540333 | 0.84 | MEN1 (0.39) | KDM4ENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1539960 | 0.84 | KDM4E (0.45) | SIGMAR1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL1540629 | 0.83 | SMN1; SMN2 (0.50) | POLBKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25087871 | 0.82 | HSD17B10 (0.48) | HSD17B10POLBSIGMAR1FKBP1ABCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |