SCHEMBL6469158

SCHEMBL6469158

CC(=O)OC(=O)CN(C(C)=O)c1ccc(O)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.36
ESR2 Q92731 2/20 0.36
PREP P48147 3/20 0.33
CELA1 Q9UNI1 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 3/20 0.33
MLYCD O95822 1/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
PDK2 Q15119 2/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
PDK1 Q15118 1/20 0.32
PDK3 Q15120 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5813341 0.85 MLYCD (0.45) ESR1ESR2SMN1; SMN2ALDH1A1MLYCD
SCHEMBL3662801 0.82 CA12 (0.47) ESR1ESR2SMN1; SMN2ALDH1A1CA12
SCHEMBL5810849 0.81 CA12 (0.45) ESR1ESR2ALDH1A1MLYCDCA12
SCHEMBL5809076 0.80 ESR1 (0.49) ESR1ESR2SMN1; SMN2ALDH1A1CA12
SCHEMBL935744 0.79 MLYCD (0.41) ESR1ESR2ALDH1A1MLYCDCA2
SCHEMBL6909286 0.77 CA2 (0.42) ESR1ESR2SMN1; SMN2ALDH1A1CA12
SCHEMBL6470888 0.75 ESR1 (0.39) ESR1ESR2SMN1; SMN2ALDH1A1MLYCD
SCHEMBL10926482 0.74 ALDH1A1 (0.48) ESR1ESR2SMN1; SMN2ALDH1A1MLYCD
SCHEMBL9645342 0.73 ESR1 (0.40) ESR1ESR2SMN1; SMN2ALDH1A1CA12
SCHEMBL27872334 0.73 ESR1 (0.40) ESR1ESR2ALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050171194-A1 Enlargement of mucocutaneous or cutaneous organs and sites with topical compositions YU RUEY J (US) 2005-08-04 US claimed
WO-2005055947-A2 ENLARGEMENT OF MUCOCUTANEOUS OR CUTANEOUS ORGANS AND SITES WITH TOPICAL COMPOSITIONS YU RUEY J (US) 2005-06-23 WO claimed
US-4182899-A Optical resolution of amino acids into optical antipodes HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-08 US claimed
EP-0001319-A1 Process for the preparation of hydroxyphenyl hydantoin and of hydroxyphenyl glycine, and compounds thus obtained BEECHAM GROUP PLC (GB) 1979-04-04 EP claimed
US-20050171194-A1 Enlargement of mucocutaneous or cutaneous organs and sites with topical compositions YU RUEY J (US) 2005-08-04 US disclosed
EP-0001319-A1 Process for the preparation of hydroxyphenyl hydantoin and of hydroxyphenyl glycine, and compounds thus obtained BEECHAM GROUP PLC (GB) 1979-04-04 EP disclosed
US-3994962-A INTERMEDIATE FOR PENICILLIN AND CEPHALOSPORIN DERIVATIVES NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1976-11-30 US disclosed