Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6469150 | 0.99 | RET (0.42) | RETKDREGFRESR1ESR2 | |
| Trifluoroacetic Acid SCHEMBL6468678 | 0.95 | HRH3 (0.46) | RETHRH3AVPR1BKCNH2EHMT2 | |
| Trifluoroacetic Acid SCHEMBL6471240 | 0.94 | RET (0.43) | RETKDREGFRAVPR1BEHMT2 | |
| Trifluoroacetic Acid SCHEMBL6470128 | 0.93 | PDK1 (0.41) | RETAVPR1BACHEEHMT2KDM4E | |
| Trifluoroacetic Acid SCHEMBL6469283 | 0.91 | HRH3 (0.39) | RETEGFRHRH3EHMT2KDM4E | |
| Trifluoroacetic Acid SCHEMBL6470902 | 0.89 | HRH3 (0.42) | KDRESR1ESR2HRH3AVPR1B | |
| Trifluoroacetic Acid SCHEMBL6467099 | 0.89 | RET (0.40) | RETEGFRHRH3AVPR1BKCNH2 | |
| Trifluoroacetic Acid SCHEMBL6471255 | 0.89 | RET (0.40) | RETKDREGFRHRH3AVPR1B | |
| SCHEMBL6469215 | 0.89 | KDR (0.41) | RETKDREGFRAVPR1BACHE | |
| Trifluoroacetic Acid SCHEMBL6469094 | 0.88 | WHR1 (0.37) | PDGFRBEHMT2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124562-A1 | Bis-quinazoline compounds for the treatment of bacterial infections | REPLIDYNE, INC. | 2005-06-09 | — | — | US | claimed |
| US-20050124562-A1 | Bis-quinazoline compounds for the treatment of bacterial infections | REPLIDYNE, INC. | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124562-A1 | Bis-quinazoline compounds for the treatment of bacterial infections | POLI, POLK, POLB | RET 4244/4885KDR 4703/4885EGFR 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.