Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 8/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAP2 | P11137 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919125 | 0.89 | GRIA2 (0.46) | GRIA2GRIA4ALDH1A1GAAHPGD | |
| SCHEMBL4921193 | 0.89 | GRIA2 (0.46) | GRIA2GRIA4ALDH1A1GAAHPGD | |
| SCHEMBL6464882 | 0.87 | MAP2 (0.43) | GRIA2GRIA4ALDH1A1GAAHPGD | |
| SCHEMBL6466109 | 0.85 | ALDH1A1 (0.59) | GRIA2GRIA4ALDH1A1GAAHPGD | |
| SCHEMBL4918452 | 0.79 | GRIA2 (0.42) | GRIA2GRIA4ALDH1A1HPGDAR | |
| SCHEMBL6466743 | 0.77 | CYP2A6 (0.44) | GRIA2GRIA4ALDH1A1GAAHPGD | |
| SCHEMBL6466967 | 0.77 | MAP2 (0.42) | GRIA2GRIA4ALDH1A1GAAHPGD | |
| SCHEMBL5362730 | 0.75 | AR (0.44) | GRIA2GRIA4ALDH1A1GAAAR | |
| SCHEMBL6468391 | 0.75 | ALDH1A1 (0.57) | GRIA2GRIA4ALDH1A1GAAHPGD | |
| SCHEMBL4918939 | 0.75 | KMT2A (0.48) | GRIA2GRIA4ALDH1A1GAAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101657-A1 | Pyrrole derivatives for preventing or treating cancer sensitive to hormones; administered with luteininzing hormone releasing hormone derivative | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2005-05-12 | — | — | US | disclosed |
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101657-A1 | Pyrrole derivatives for preventing or treating cancer sensitive to hormones; administered with luteininzing hormone releasing hormone derivative | SHBG, PRLHR, FSHR | GRIA2 715/4885GRIA4 665/4885ALDH1A1 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.