Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727862 | 0.99 | NPSR1 (0.34) | LMNANPSR1GAAKMT2AMAOA | |
| SCHEMBL728311 | 0.71 | — | — | |
| SCHEMBL906549 | 0.63 | — | — | |
| SCHEMBL6469289 | 0.59 | HDAC8 (0.36) | LMNANPSR1GAAKMT2A | |
| SCHEMBL7622820 | 0.59 | HDAC8 (0.36) | LMNANPSR1GAAKMT2A | |
| SCHEMBL727844 | 0.57 | HDAC8 (0.37) | LMNANPSR1GAAKMT2A | |
| SCHEMBL12218523 | 0.55 | NPSR1 (0.96) | LMNANPSR1GAAKMT2AMAOA | |
| SCHEMBL1946708 | 0.54 | NPSR1 (0.72) | LMNANPSR1KMT2A | |
| SCHEMBL29010922 | 0.54 | HDAC8 (0.42) | LMNANPSR1GAAKMT2A | |
| SCHEMBL24618011 | 0.53 | HDAC8 (0.61) | LMNANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509552-A1 | SOLID, PARTICULATED, SPRAY DRIED, HETEROGENOUS CATALYST COMPOSITION | Univation Technologies LLC (US) | 2005-03-02 | — | — | EP | disclosed |
| EP-1412365-A1 | SALT OF LEWIS ACID/ACID ADDUCTS AND CATALYST ACTIVATORS THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003102037-A1 | SOLID, PARTICULATED, SPRAY DRIED, HETEROGENOUS CATALYST COMPOSITION | UNIVATION TECHNOLOGIES, LLC (US) | 2003-12-11 | — | — | WO | disclosed |
| WO-2003010171-A1 | SALT OF LEWIS ACID/ACID ADDUCTS AND CATALYST ACTIVATORS THEREFROM | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2003-02-06 | — | — | WO | disclosed |