Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469289 | 0.99 | HDAC8 (0.36) | HDAC8HDAC6KMT2AMEN1LMNA | |
| SCHEMBL7622820 | 0.99 | HDAC8 (0.36) | HDAC8HDAC6KMT2AMEN1LMNA | |
| SCHEMBL5968790 | 0.87 | — | — | |
| SCHEMBL5968791 | 0.87 | — | — | |
| SCHEMBL5968778 | 0.84 | HPGD (0.37) | HDAC8HDAC6LMNARAB9ASMN1; SMN2 | |
| SCHEMBL5969036 | 0.84 | HPGD (0.37) | HDAC8HDAC6LMNARAB9ASMN1; SMN2 | |
| SCHEMBL7246533 | 0.75 | P2RX7 (0.38) | KMT2ALMNANPSR1RAB9ASMN1; SMN2 | |
| SCHEMBL7924767 | 0.72 | ALDH1A1 (0.33) | KMT2ARAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL8073123 | 0.69 | KMT2A (0.40) | HDAC8HDAC6KMT2AMEN1LMNA | |
| SCHEMBL8168259 | 0.69 | HDAC8 (0.38) | HDAC8HDAC6KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4722287-B2 | — | — | 2011-07-13 | — | — | JP | claimed |
| EP-1056752-A1 | CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS | THE DOW CHEMICAL COMPANY (US) | 2000-12-06 | — | — | EP | claimed |
| WO-1999042467-A1 | CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS | THE DOW CHEMICAL COMPANY (US) | 1999-08-26 | — | — | WO | claimed |