SCHEMBL58444

SCHEMBL58444

Cc1ccc(C)c(P(=O)(C(=O)c2c(Cl)cccc2Cl)C(=O)c2c(Cl)cccc2Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 2/20 0.39
RAB9A P51151 2/20 0.38
ALDH1A1 P00352 2/20 0.38
TAS1R3 Q7RTX0 2/20 0.38
TAS1R1 Q7RTX1 2/20 0.38
TAS1R2 Q8TE23 2/20 0.38
S1PR4 O95977 2/20 0.38
TYK2 P29597 1/20 0.38
HDAC8 Q9BY41 2/20 0.37
KCNK3 O14649 1/20 0.37
KCNK9 Q9NPC2 1/20 0.37
ABCB1 P08183 1/20 0.37
PTGS2 P35354 2/20 0.36
HDAC6 Q9UBN7 1/20 0.36
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29365063 1.00 GAA (0.40) GAAPOLBMAPTRAB9AALDH1A1
SCHEMBL11062242 0.88 GAA (0.40) GAAPOLBMAPTRAB9AALDH1A1
SCHEMBL6469382 0.86 S1PR4 (0.43) GAAMAPTS1PR4HDAC8KCNK3
SCHEMBL29372199 0.83 MEN1 (0.38) GAAPOLBRAB9ATAS1R3TAS1R1
SCHEMBL58468 0.83 MEN1 (0.38) GAAPOLBRAB9ATAS1R3TAS1R1
SCHEMBL29372058 0.81 GAA (0.39) GAAMAPTRAB9ATAS1R3TAS1R1
SCHEMBL58579 0.81 GAA (0.39) GAAMAPTRAB9ATAS1R3TAS1R1
SCHEMBL711411 0.79 NPC1 (0.46) GAAPOLBMAPTRAB9AALDH1A1
SCHEMBL56980 0.77 TAS1R3 (0.42) GAAPOLBRAB9AALDH1A1TAS1R3
SCHEMBL29494122 0.77 TAS1R3 (0.42) GAAPOLBRAB9AALDH1A1TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051500-A1 RADIATION-CURABLE COMPOSITION MARABU GMBH & CO. KG (DE) 2025-02-13 US claimed
EP-4506424-A1 RADIATION-CURABLE COMPOSITION Marabu GmbH & Co. KG (DE) 2025-02-12 EP claimed
US-12024136-B2 Ultra-fast curing scratch-resistant headlight restoration coating ILLINOIS TOOL WORKS INC. (US) 2024-07-02 US claimed
US-20240173212-A1 HIGH TRANSPARENCY AND LONG-RELEASE DENTAL RESIN COMPOSITION CONTAINING CORE-SHELL POROUS STRUCTURED NANOPARTICLES AND METHOD FOR PREPARING THE SAME JNP Nature Co., Ltd. (KR) 2024-05-30 US claimed
CN-118078642-A High-transparency and long-term release dental resin composition comprising core-shell porous structured nanoparticles and method for preparing same JNP自然股份有限公司 2024-05-28 CN claimed
EP-4056658-A1 RADIATION-CURABLE COMPOUND Marabu GmbH & Co. KG (DE) 2022-09-14 EP claimed
EP-0184095-B1 BISACYLPHOSPHINOXIDES, THEIR PREPARATION AND USE ESPE Stiftung & Co Produktions- und Vertriebs KG (DE) 1989-07-05 EP claimed
US-4737593-A PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY Fabrik Pharmazeutischer Praparate (DE) 1988-04-12 US claimed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-3861977-B1 (METH)ACRYLATE, MONOMER COMPOSITION, MOLDED BODY, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2026-05-06 EP disclosed
US-12617887-B2 Resin composition for stereolithography KURARAY NORITAKE DENTAL INC. (JP) 2026-05-05 US disclosed
EP-3862373-B1 RESIN COMPOSITION FOR OPTICAL SHAPING KURARAY NORITAKE DENTAL INC (JP) 2026-04-22 EP disclosed
EP-3419051-B1 CURABLE RESIN COMPOSITION AND FAN OUT TYPE WAFER LEVEL PACKAGE TAIYO HOLDINGS CO LTD (JP) 2026-04-08 EP disclosed
EP-4722266-A1 STEREOLITHOGRAPHIC RESIN COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-08 EP disclosed
EP-1002817-A2 Photocurable composition SHOWA DENKO KABUSHIKI KAISHA (JP) 2000-05-24 EP disclosed
EP-0915136-A1 Photocurable paint composition for road markings SHOWA DENKO KABUSHIKI KAISHA (JP) 1999-05-12 EP disclosed
EP-0825201-A1 Photocurable composition and curing process therefor SHOWA DENKO KABUSHIKI KAISHA (JP) 1998-02-25 EP disclosed
US-4868091-A USING A BISACYLPHOSPHINE OXIDE PHOTOINITIATOR, UNSATURATED COMPOUND AND POLYMERIC BINDER; SHORT EXPOSURE TIME; NEWSPAPER PRINTING BASF AKTIENGESELLSCHAFT (DE) 1989-09-19 US disclosed
US-4792632-A ADDITION POLYMER PHOTOINITIATORS ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) 1988-12-20 US disclosed
US-4737593-A PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY Fabrik Pharmazeutischer Praparate (DE) 1988-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL GAA 3536/4885POLB 4114/4885MAPT 4304/4885
US-12617887-B2 Resin composition for stereolithography MAT2B, MAT1A, ARCN1 GAA 2248/4885POLB 1411/4885MAPT 2407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.