Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MLYCD | O95822 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232842 | 0.93 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPTMLYCDL3MBTL1 | |
| SCHEMBL6802252 | 0.89 | HPGD (0.69) | ALDH1A1HPGDMAPTMLYCDL3MBTL1 | |
| Alcohol SCHEMBL28456385 | 0.83 | ALDH1A1 (0.79) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL20645776 | 0.83 | MLYCD (0.53) | ALDH1A1HPGDMAPTMLYCDL3MBTL1 | |
| SCHEMBL19894769 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPTMLYCDL3MBTL1 | |
| Propionic Acid SCHEMBL28665177 | 0.82 | ALDH1A1 (0.76) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL15768219 | 0.81 | HPGD (0.48) | ALDH1A1HPGDMAPTMLYCDL3MBTL1 | |
| SCHEMBL63361 | 0.81 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2 | |
| Terephthalic Acid SCHEMBL11068404 | 0.81 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL5703500 | 0.81 | HPGD (0.73) | ALDH1A1HPGDMAPTMLYCDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501513-A2 | COMPOSITIONS AND METHODS FOR COMBATING LOWER URINARY TRACT DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONISTS | Ardent Pharmaceuticals, Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003094853-A2 | COMPOSITIONS AND METHODS FOR COMBATING LOWER URINARY TRACT DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONISTS | ARDENT PHARMACEUTICALS, INC. (US) | 2003-11-20 | — | — | WO | disclosed |