SCHEMBL6469715

SCHEMBL6469715

Cl[Ti](Cl)(C1C=Cc2ccccc21)(C1C=Cc2ccccc21)[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8605230 0.84 SIGMAR1 (0.31)
SCHEMBL7600844 0.80 SIGMAR1 (0.32) HTR6HTR2A
SCHEMBL2534841 0.79 BRD4 (0.33) HTR6HTR2A
SCHEMBL7628304 0.79 HTR6 (0.30) HTR6HTR2A
SCHEMBL5852770 0.77
SCHEMBL7752430 0.75 HTR2A (0.33) HTR6HTR2A
SCHEMBL7635150 0.75 SIGMAR1 (0.35) HTR6HTR2A
SCHEMBL6702472 0.75 SIGMAR1 (0.34) HTR2A
SCHEMBL5854622 0.75 MEN1 (0.31)
SCHEMBL5853329 0.74 ATM (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0881232-B1 Catalyst for olefin polymerization and process for the production of an olefin polymer TOSOH CORP (JP) 2005-03-16 EP disclosed
EP-0755971-B1 Molding resin, composition containing the same, and processes for producing them TOSOH CORP (JP) 2002-03-06 EP disclosed
EP-0727443-B1 Catalyst for olefin polymerization and process for producing olefin polymers TOSOH CORP (JP) 2001-01-17 EP disclosed
US-6034187-A Catalyst for olefin polymerization and process for production of olefin polymer TOSOH CORPORATION (JP) 2000-03-07 US disclosed
US-5962599-A ETHYLENE-HEXENE COPOLYMER TOSOH CORPORATION (JP) 1999-10-05 US disclosed
EP-0881232-A1 Catalyst for olefin polymerization and process for production of olefin polymer TOSOH CORPORATION (JP) 1998-12-02 EP disclosed
US-5807938-A Catalyst for olefin polymerization and process for producing olefin polymers TOSOH CORPORATION (JP) 1998-09-15 US disclosed
US-5770752-A Process for reducing the concentration of by-products in product mixtures TARGOR GMBH (DE) 1998-06-23 US disclosed
US-5712365-A Process for producing ethylene alpha-olefin copolymer TOSOH CORPORATION (JP) 1998-01-27 US disclosed
EP-0730003-B1 Polypropylene resin composition and molded product TOSOH CORP (JP) 1997-12-29 EP disclosed
EP-0628574-B1 Olefin polymerization catalyst and olefin polymerization process TOSOH CORP (JP) 1997-12-03 EP disclosed
US-5608008-A ETHYLENE-A-OLEFIN COPOLYMER ELASTOMER TOSOH CORPORATION (JP) 1997-03-04 US disclosed
EP-0755971-A2 Molding resin, composition containing the same, and processes for producing them Tosoh Corporation (JP) 1997-01-29 EP disclosed
EP-0730003-A1 Polypropylene resin composition and molded product Tosoh Corporation (JP) 1996-09-04 EP disclosed
EP-0727443-A1 Catalyst for olefin polymerization and process for producing olefin polymers Tosoh Corporation (JP) 1996-08-21 EP disclosed
EP-0628574-A1 Olefin polymerization catalyst and olefin polymerization process TOSOH CORPORATION (JP) 1994-12-14 EP disclosed