Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602896 | 0.85 | SIGMAR1 (0.31) | SIGMAR1BRD4CCL2HTR6HTR2A | |
| SCHEMBL7601265 | 0.81 | BRD4 (0.34) | SIGMAR1BRD4CCL2HTR6HTR2A | |
| SCHEMBL6469715 | 0.80 | HTR6 (0.31) | HTR6HTR2A | |
| SCHEMBL7628304 | 0.79 | HTR6 (0.30) | HTR6HTR2A | |
| SCHEMBL7633085 | 0.77 | HTR2A (0.34) | SIGMAR1BRD4CCL2HTR6HTR2A | |
| SCHEMBL7635150 | 0.75 | SIGMAR1 (0.35) | SIGMAR1HTR6HTR2A | |
| SCHEMBL796825 | 0.75 | KDM4E (0.33) | SIGMAR1HTR2A | |
| SCHEMBL8605230 | 0.74 | SIGMAR1 (0.31) | SIGMAR1BRD4CCL2 | |
| SCHEMBL7924385 | 0.73 | GPR3 (0.30) | — | |
| SCHEMBL3383375 | 0.73 | BRD4 (0.36) | SIGMAR1BRD4CCL2HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| EP-0849288-B1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORP (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |
| US-5906955-A | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1999-05-25 | — | — | US | disclosed |
| EP-0849288-A1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1998-06-24 | — | — | EP | disclosed |