SCHEMBL6469773

SCHEMBL6469773

CC(C(=O)O)S(=O)(=O)c1ccc(C(=O)CBr)cc1

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 9/20 0.50
PTPN1 P18031 5/20 0.48
CA2 P00918 6/20 0.40
CA1 P00915 3/20 0.40
TAS2R14 Q9NYV8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6470795 0.81 SLC1A3 (0.49) CA2CA1
SCHEMBL8013573 0.79 MMP2 (0.55) CA2CA1
SCHEMBL22206134 0.77 CA1 (0.54) CA2CA1
SCHEMBL28230363 0.77 CA1 (0.54) CA2CA1
SCHEMBL125350 0.77 GSR (0.59) GSK3BPTPN1
SCHEMBL1200588 0.76 CA1 (0.53) CA2CA1
SCHEMBL23049688 0.76 CA2 (0.48) CA2CA1TAS2R14
SCHEMBL23049767 0.76 CA2 (0.48) CA2CA1TAS2R14
SCHEMBL27214045 0.75 NPSR1 (0.54) GSK3BPTPN1
SCHEMBL16232170 0.75 MMP2 (0.50) CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005110955-A1 SUBSTITUTED ACETOPHENOME AS MS REAGENTS GE HEALTHCARE BIO-SCIENCES AB (SE) 2005-11-24 WO disclosed