Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 8/20 | 0.53 |
| ▸ | MMP13 | P45452 | 8/20 | 0.53 |
| ▸ | MMP9 | P14780 | 7/20 | 0.53 |
| ▸ | MMP3 | P08254 | 6/20 | 0.53 |
| ▸ | MMP7 | P09237 | 6/20 | 0.53 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28230363 | 0.82 | CA1 (0.54) | MMP2CA12MMP1MMP13MMP9 | |
| SCHEMBL22206134 | 0.82 | CA1 (0.54) | MMP2CA12MMP1MMP13MMP9 | |
| SCHEMBL1200588 | 0.82 | CA1 (0.53) | MMP2CA12MMP1MMP13MMP9 | |
| SCHEMBL27183057 | 0.81 | MMP2 (0.51) | MMP2CA12CA14MMP1MMP13 | |
| SCHEMBL16232170 | 0.81 | MMP2 (0.50) | MMP2CA12MMP1MMP13MMP9 | |
| SCHEMBL6470795 | 0.79 | SLC1A3 (0.49) | CA12KMT2ACA2CA1CA9 | |
| SCHEMBL6469773 | 0.79 | GSK3B (0.50) | CA2CA1 | |
| SCHEMBL23049767 | 0.78 | CA2 (0.48) | MMP2CA12MMP9KMT2ACA2 | |
| SCHEMBL23049688 | 0.78 | CA2 (0.48) | MMP2CA12MMP9KMT2ACA2 | |
| SCHEMBL7352846 | 0.78 | MMP13 (0.60) | MMP2MMP1MMP13MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6118001-A | ANTICANCER AGENT; ANTIARTHRITIC AGENT | DARWIN DISCOVERY, LTD. (GB) | 2000-09-12 | — | — | US | disclosed |