⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024430 | 0.86 | — | — | |
| SCHEMBL27566558 | 0.86 | — | — | |
| SCHEMBL178388 | 0.84 | — | — | |
| SCHEMBL6927442 | 0.84 | — | — | |
| SCHEMBL367180 | 0.84 | GNAO1 (0.49) | — | |
| SCHEMBL11122184 | 0.82 | GNAO1 (0.51) | — | |
| SCHEMBL10633517 | 0.82 | GNAO1 (0.51) | — | |
| SCHEMBL15743617 | 0.82 | GNAO1 (0.51) | — | |
| SCHEMBL1189178 | 0.82 | GNAO1 (0.51) | — | |
| SCHEMBL15232418 | 0.82 | GNAO1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115697-B | Method for producing propylene from propane | BASF AG | 2010-09-29 | — | — | CN | claimed |
| CN-101115697-A | Method for producing propylene from propane | BASF AG (DE) | 2008-01-30 | — | — | CN | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | claimed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | claimed |
| EP-4400504-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CN) | 2024-07-17 | — | — | EP | disclosed |
| CN-113422094-B | Gel concentration difference power generation device and preparation method thereof | 李慧虹 | 2023-03-24 | — | — | CN | disclosed |
| EP-3267794-B1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | UNIV YALE (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10611765-B2 | Pyrrolopyrimidine derivatives as Mps1/TTK kinase inhibitors | OHIO STATE INNOVATION FOUNDATION | 2020-04-07 | — | — | US | disclosed |
| US-20190106422-A1 | PYRROLOPYRIMIDINE DERIVATIVES AS MPS1/TTK KINASE INHIBITORS | OHIO STATE INNOVATION FOUNDATION | 2019-04-11 | — | — | US | disclosed |
| US-20180111919-A1 | NEW FYN KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2018-04-26 | — | — | US | disclosed |
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | disclosed |
| EP-0383200-A2 | Process for the production of photopolymerised relief-printing plates with non-tacky surface | BASF Aktiengesellschaft (DE) | 1990-08-22 | — | — | EP | disclosed |
| US-4900795-A | PHOTOPOLMERIZABLE POLYMER COMPRISING ETHYLENE, (METH)ACRYLIC ACID AND VINYL OR ACRYLATE MONOMER NEUTRALIZED BY A CYCLIC AMINE OR HYDROXY-CONTAINING AMINE; PHOTORESISTS; PRINTING PLATES; OZONE RESISTANCE; ELONGATION; TENSILE STRENGTH | BASF AKTIENGESELLSCHAFT (DE) | 1990-02-13 | — | — | US | disclosed |
| US-4824849-A | α2 -adrenoceptor antagonistic arylquinolizines | MERCK & CO., INC. (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0293750-A2 | Polymer ammonium salts | BASF Aktiengesellschaft (DE) | 1988-12-07 | — | — | EP | disclosed |
| US-4710504-A | Anti-depressant spiro hexahydro arylquinolizine derivatives, composition, and method of use therefor | MERCK & CO., INC. (US) | 1987-12-01 | — | — | US | disclosed |
| EP-0204254-A2 | Substituted hexahydro arylquinolizines, processes for their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1986-12-10 | — | — | EP | disclosed |