Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16806094 | 0.88 | POLB (0.45) | ELANEPOLBHTTTDP1APEX1 | |
| SCHEMBL65218 | 0.87 | POLB (0.51) | ELANEPOLBHTTTDP1APEX1 | |
| SCHEMBL6668640 | 0.85 | POLB (0.56) | ELANEPOLBHTTTDP1APEX1 | |
| SCHEMBL1123797 | 0.85 | ELANE (0.44) | ELANEPOLBHTTTDP1APEX1 | |
| SCHEMBL6290863 | 0.84 | POLB (0.44) | ELANEPOLBHTTTDP1APEX1 | |
| SCHEMBL17510055 | 0.84 | POLB (0.48) | ELANEPOLBHTTTDP1APEX1 | |
| SCHEMBL620722 | 0.84 | POLB (0.48) | ELANEPOLBHTTTDP1APEX1 | |
| SCHEMBL14173071 | 0.83 | ELANE (0.56) | ELANEPOLBHTTTDP1KMT2A | |
| SCHEMBL30971 | 0.83 | ELANE (0.56) | ELANEPOLBHTTTDP1KMT2A | |
| SCHEMBL17867710 | 0.82 | POLB (0.50) | ELANEPOLBHTTTDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050179149-A1 | Mould, a method of manufacturing the same as well as its use | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2005-08-18 | — | — | US | disclosed |
| EP-1499487-A1 | A MOULD, A METHOD OF MANUFACTURING THE SAME AS WELL AS ITS USE | Koninklijke Philips Electronics N.V. (NL) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003084727-A1 | A MOULD, A METHOD OF MANUFACTURING THE SAME AS WELL AS ITS USE | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2003-10-16 | — | — | WO | disclosed |