Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700802 | 1.00 | LPAR3 (0.45) | LPAR3LPAR2LPAR1NAAACES2 | |
| SCHEMBL3913988 | 1.00 | LPAR3 (0.45) | LPAR3LPAR2LPAR1NAAACES2 | |
| SCHEMBL9660836 | 1.00 | LPAR3 (0.45) | LPAR3LPAR2LPAR1NAAACES2 | |
| SCHEMBL700500 | 1.00 | LPAR3 (0.45) | LPAR3LPAR2LPAR1NAAACES2 | |
| SCHEMBL9660637 | 1.00 | LPAR3 (0.45) | LPAR3LPAR2LPAR1NAAACES2 | |
| SCHEMBL700752 | 1.00 | LPAR3 (0.45) | LPAR3LPAR2LPAR1NAAACES2 | |
| SCHEMBL706907 | 0.98 | — | — | |
| SCHEMBL4241992 | 0.92 | HTT (0.50) | LPAR3LPAR2LPAR1NAAACES2 | |
| SCHEMBL702719 | 0.90 | — | — | |
| SCHEMBL1689825 | 0.88 | LPAR3 (0.50) | LPAR3LPAR2LPAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050058725-A1 | Combination therapy including a matrix metalloproteinase inhibitor and an antineoplastic agent | MCKEARN JOHN P (US) | 2005-03-17 | — | — | US | disclosed |
| US-6506393-B2 | Administering phosphocholine compound; leishmaniasis treatment | ZENTARIS AG (DE) | 2003-01-14 | — | — | US | disclosed |
| EP-1135193-A1 | AGENTS PROVIDED FOR TREATING TUMORS, BASED ON LIPOSOMES, AND CONTAINING TAMOXIFEN | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) | 2001-09-26 | — | — | EP | disclosed |
| US-6254879-B1 | QUATERNARIUMAMINOETHYLPHOSPHATES | Max-Planck-Gessellschaft zun Förderung der Wissenschaften e.V. (DE) | 2001-07-03 | — | — | US | disclosed |
| WO-2000033917-A1 | AGENTS PROVIDED FOR TREATING TUMORS, BASED ON LIPOSOMES, AND CONTAINING TAMOXIFEN | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2000-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050058725-A1 | Combination therapy including a matrix metalloproteinase inhibitor and an antineoplastic agent | MMP3, MMP10, MMP25 | LPAR3 1332/4885LPAR2 1094/4885LPAR1 1135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.