Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776051 | 1.00 | NPC1 (0.57) | NPC1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL8912996 | 0.91 | CA12 (0.56) | MAPTRAB9AKMT2AMEN1KDM4E | |
| SCHEMBL9483024 | 0.89 | MAPT (0.55) | NPC1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL7776170 | 0.88 | MAPT (0.51) | NPC1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL8659346 | 0.87 | HSD17B10 (0.67) | NPC1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL7774810 | 0.87 | HSD17B10 (0.67) | NPC1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL7621149 | 0.84 | ALDH1A1 (0.63) | NPC1MAPTKMT2AMEN1LMNA | |
| SCHEMBL8657412 | 0.84 | TP53 (0.55) | NPC1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL6295675 | 0.84 | SIRT1 (0.60) | NPC1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL6295620 | 0.84 | MEN1 (0.65) | NPC1RAB9AKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788889-B1 | A thermal sensitive recording sheet | JUJO PAPER CO LTD (JP) | 2001-08-08 | — | — | EP | disclosed |
| EP-0788889-A2 | A thermal sensitive recording sheet | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |