Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2212154 | 0.90 | HSD17B10 (0.60) | KDM4EHTTNPSR1ALDH1A1HSD17B10 | |
| SCHEMBL12106076 | 0.85 | HTT (0.62) | KDM4EHTTNPSR1ALDH1A1HSD17B10 | |
| SCHEMBL7869978 | 0.85 | HTT (0.62) | KDM4EHTTNPSR1ALDH1A1HSD17B10 | |
| SCHEMBL12103715 | 0.83 | HTT (0.59) | KDM4EHTTNPSR1ALDH1A1KMT2A | |
| SCHEMBL20796169 | 0.81 | ALDH1A1 (0.52) | KDM4EHTTALDH1A1KMT2AMEN1 | |
| SCHEMBL7704838 | 0.81 | ALDH1A1 (0.67) | KDM4EHTTNPSR1ALDH1A1HSD17B10 | |
| SCHEMBL10419192 | 0.81 | MMP2 (0.59) | ALDH1A1HSD11B1POLB | |
| SCHEMBL7075505 | 0.81 | HSD11B1 (0.62) | KDM4EHTTNPSR1ALDH1A1HSD17B10 | |
| SCHEMBL25128778 | 0.80 | KMT2A (0.76) | HTTALDH1A1HSD17B10KMT2ALMNA | |
| SCHEMBL7868867 | 0.80 | ALDH1A1 (0.65) | KDM4EHTTNPSR1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110955-A1 | SUBSTITUTED ACETOPHENOME AS MS REAGENTS | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2005-11-24 | — | — | WO | disclosed |