Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819515 | 0.81 | HTR2A (0.39) | HTR2ATAAR1L3MBTL1KDM4EHRH1 | |
| SCHEMBL5642404 | 0.81 | HTR2A (0.54) | HTR2ATAAR1HRH1HPGDSLC6A2 | |
| SCHEMBL9531756 | 0.80 | SLC6A2 (0.50) | HTR2ATAAR1L3MBTL1KDM4EHRH1 | |
| SCHEMBL11531757 | 0.76 | KMT2A (0.35) | HTR2ATAAR1L3MBTL1KDM4ESLC6A2 | |
| SCHEMBL7510243 | 0.76 | KMT2A (0.44) | L3MBTL1KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3813663 | 0.74 | TBXAS1 (0.37) | HTR2AHRH1 | |
| SCHEMBL7438313 | 0.74 | SLC6A2 (0.40) | HPGDNISCHSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11528941 | 0.73 | CYP1A2 (0.42) | TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9384051 | 0.73 | DPP4 (0.39) | KMT2AATM | |
| SCHEMBL8090152 | 0.73 | KMT2A (0.33) | L3MBTL1KDM4ESLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603890-A1 | TETRAZOLE AND OXADIAZOLONE SUBSTITUTED &bgr;-AMINO ACID DERIVATIVES | Warner-Lambert Company LLC (US) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004078734-A1 | TETRAZOLE AND OXADIAZOLONE SUBSTITUTED β-AMINO ACID DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2004-09-16 | — | — | WO | disclosed |